Solid Phase Extraction (SPE) ndi chitsanzo chaukadaulo waukadaulo wopangidwa kuyambira pakati pa 1980s.Amapangidwa ndi kuphatikiza kwa madzi-olimba m'zigawo ndi madzi chromatography.Makamaka ntchito kulekana, kuyeretsa ndi kulemeretsa zitsanzo.Cholinga chachikulu ndikuchepetsa kusokoneza kwa matrix ndikuwongolera kuzindikira.

Kutengera chiphunzitso cha chromatography yamadzi-solid, ukadaulo wa SPE umagwiritsa ntchito kutsatsa kosankha ndikusankha kuti alemere, kulekanitsa ndi kuyeretsa zitsanzo.Ndi thupi m'zigawo ndondomeko kuphatikizapo madzi ndi olimba magawo;ingathenso kuyerekezedwa ndi kuonedwa ngati njira yosavuta ya chromatographic.
Chithunzi chojambula cha chipangizo cholimba chochotsa gawo
SPE ndiye mfundo yolekanitsa ya chromatography yamadzimadzi pogwiritsa ntchito ma adsorption osankhidwa ndi kutulutsa kosankha.Njira yomwe imagwiritsidwa ntchito kwambiri ndikudutsa njira yamadzimadzi kudzera mu adsorbent, kusunga chinthucho kuti chiyesedwe, ndiyeno gwiritsani ntchito chosungunulira cha mphamvu yoyenera kutulutsa zonyansa, ndiyeno mwachangu kutulutsa chinthucho kuti chiyesedwe ndi pang'ono. zosungunulira, kuti akwaniritse cholinga cha kulekana mofulumira, kuyeretsedwa ndi ndende.Ndizothekanso kusankha adsorb zosokoneza ndikulola kuti chinthu choyezedwa chituluke;kapena adsorb zonyansa ndi zinthu kuyeza pa nthawi yomweyo, ndiyeno ntchito zosungunulira abwino kusankha elute chinthu anayeza.
The extractant wa olimba gawo m'zigawo njira ndi olimba, ndi ntchito yake mfundo zachokera mfundo yakuti zigawo zikuluzikulu kuyeza ndi coexisting akusokoneza zigawo mu madzi chitsanzo ndi mphamvu zosiyana pa olimba-gawo m'zigawo wothandizira, kotero kuti iwo. amalekana wina ndi mzake.Solid gawo m'zigawo wothandizira ndi filler wapadera munali C18 kapena C8, nitrile, amino ndi magulu ena.