Alumina-N Column Plates for Solid Phase Extraction

Alumina is a typical Lewis acid that does not have two electrons in the center of the aluminum atom, it is a strong polar adsorbent similar to silica gel; It is available in three high activity levels: acidic, basic, and neutral; alumina also has a special effect on the π-electrons of aromatic hydrocarbons; and it is more stable than silica gel under high pH conditions. The main confinement mechanisms are the Lewis acid-base interaction, the polar interaction, and ion exchange.
B&M® Alumina-N (pH=7.5) is also a strongly polar adsorbent. At high pH, alumina is more stable than silica gel with unbound functional groups. Smaller particles provide high extraction efficiency, which is why small columns (50 mg) are most often used. This adsorbent has an electrically neutral surface and promotes the retention of electron-rich compounds such as aromatics and aliphatic amines. It is also capable of holding compounds containing electronegative groups (e.g., functional groups containing atoms such as oxygen, phosphorus, and sulfur). Alumina-N can be used for the extraction and separation of polar and non-polar substances in water-soluble and non-water-soluble samples, respectively.