Oligonucleotide (Oligonucleotide), gabaɗaya yana nufin guntun polynucleotide madaidaiciya na ragowar nucleotide 2-10 waɗanda ke da alaƙa da haɗin phosphodiester, amma lokacin da aka yi amfani da wannan kalmar, adadin ragowar nucleotide Babu ƙaƙƙarfan ƙa'idodi.A cikin wallafe-wallafen da yawa, ƙwayoyin polynucleotide da ke ɗauke da ragowar nucleotide 30 ko fiye kuma ana kiran su oligonucleotides.Ana iya haɗa Oligonucleotides ta atomatik ta kayan aiki.Za a iya amfani da su azaman abubuwan da aka haɗa DNA, binciken kwayoyin halitta, da sauransu, kuma suna da fa'idar amfani da yawa a cikin binciken ilimin halittu na zamani.

aikace-aikace

Yawancin lokaci ana amfani da Oligonucleotides azaman bincike don tantance tsarin DNA ko RNA, kuma ana amfani dashi a cikin matakai kamar guntuwar kwayoyin halitta, electrophoresis, da fluorescence a cikin haɓakar yanayi.

Ana iya amfani da DNA ɗin da aka haɗa ta oligonucleotide a cikin sarkar polymerization dauki, wanda zai iya haɓakawa da tabbatar da kusan dukkanin gutsuttsuran DNA.A cikin wannan tsari, ana amfani da oligonucleotide azaman maɗaukaki don haɗawa tare da lakabin juzu'i mai alaƙa a cikin DNA don yin kwafin DNA..

Ana amfani da oligonucleotides na tsari don hana ɓarna na RNA kuma ya hana a fassara su cikin sunadaran, wanda zai iya taka wata rawa wajen dakatar da ayyukan ƙwayoyin cutar kansa.