Oligonucleotide (Oligonucleotide), guud ahaan waxa loola jeedaa jajab toosan oo polynucleotide ah oo ah 2-10 hadhaaga nucleotide ee ku xidhan bonds fosfodiester, laakiin marka ereygan la isticmaalo, tirada haraaga nucleotide Ma jiraan xeerar adag.Suugaano badan, molecules polynucleotide oo ka kooban 30 ama ka badan haraaga nucleotide ayaa sidoo kale loo yaqaan oligonucleotides.Oligonucleotides waxaa si toos ah u soo saari kara qalab.Waxa loo isticmaali karaa sidii hore-u-samaynta DNA-ga, baadhitaannada hidda-wadaha, iwm., waxaanay leeyihiin adeegsi ballaadhan oo xagga cilmi-baadhista bayooloojiyada molecular ee casriga ah.

codsi

Oligonucleotides ayaa inta badan loo isticmaalaa sidii baaritaanno si loo go'aamiyo qaab dhismeedka DNA ama RNA, waxaana loo isticmaalaa hababka sida chip hidde-sideyaasha, electrophoresis, iyo fluorescence in situ hybridization.

DNA-da uu sameeyay oligonucleotide waxaa loo isticmaali karaa falcelinta silsiladda polymerization, taas oo xoojin karta oo xaqiijin karta dhammaan jajabyada DNA-da.Geedi socodkan, oligonucleotide waxa loo istcmaalay sidii curiye si loogu daro jajabka dhammaystirka ah ee calaamadaysan ee DNA si loo sameeyo nuqul DNA ah..

Oligonucleotides nidaamsan ayaa loo isticmaalaa in lagu xakameeyo jajabyada RNA oo looga hortago in loo turjumo borotiinka, taas oo door gaar ah ka ciyaari karta joojinta dhaqdhaqaaqa unugyada kansarka.