Zearalenone (ZEN)tseem hu ua F-2 toxin.Nws yog tsim los ntawm ntau yam fusarium fungi xws li Graminearum, Culmorum thiab Crookwellense.Fungal toxins tso tawm rau hauv av ib puag ncig.Cov qauv tshuaj ntawm ZEN tau txiav txim los ntawm Urry hauv xyoo 1966 siv nuclear magnetic resonance, classical chemistry thiab mass spectrometry, thiab tau lub npe: 6-(10-hydroxy-6-oxo-trans-1-decene)-β-Ranoic acid-lactone. .Tus txheeb ze molecular loj ntawm ZEN yog 318, lub melting point yog 165 ° C, thiab nws muaj zoo thermal stability.Nws yuav tsis decompose thaum rhuab ntawm 120 ° C rau 4 teev;ZEN muaj cov yam ntxwv fluorescence thiab tuaj yeem kuaj tau los ntawm fluorescence detector;ZEN yuav tsis raug kuaj pom hauv dej, S2C thiab CC14 Dissolve;Nws yog ib qho yooj yim rau yaj hauv alkali daws xws li sodium hydroxide thiab organic solvents xws li methanol.ZEN ua phem rau cov nplej thiab lawv cov khoom los ntawm thoob plaws lub ntiaj teb, ua rau muaj kev puas tsuaj loj rau kev cog qoob loo thiab cog qoob loo, thiab tseem ua rau muaj kev hem thawj loj rau kev nyab xeeb khoom noj.

Tus qauv txwv ntawm Zen hauv zaub mov thiab pub

ZearalenoneCov pa phem tsis tsuas yog txo cov khoom ua liaj ua teb zoo thiab pub, tab sis kuj ua rau poob loj rau kev loj hlob ntawm kev lag luam.Nyob rau tib lub sijhawm, tib neeg kev noj qab haus huv tseem yuav tshwm sim los ntawm kev noj ZEN cov pa phem lossis cov khoom seem ntawm cov nqaij thiab cov khoom siv mis nyuj thiab lwm yam khoom noj los ntawm tsiaj.Thiab raug hem.kuv lub teb chaws "GB13078.2-2006 Feed Hygiene Standard" xav kom ZEN cov ntsiab lus ntawm zearalenone nyob rau hauv compound pub thiab pob kws yuav tsum tsis txhob ntau tshaj 500 μg / kg.Raws li qhov yuav tsum tau ua ntawm qhov tseeb "GB 2761-2011 Mycotoxins hauv Cov Khoom Noj Txwv" tau tshaj tawm xyoo 2011, cov ntsiab lus ntawm zearalenone ZEN hauv cov nplej thiab lawv cov khoom yuav tsum tsawg dua 60μg / kg.Raws li "Feed Hygiene Standards" uas tau hloov kho, qhov kev txwv nruj tshaj plaws ntawm zearalenone hauv kev sib xyaw pub rau piglets thiab cov tub ntxhais hluas sows yog 100 μg / kg.Tsis tas li ntawd, Fabkis tau hais tias qhov tso cai ntawm zearalenone hauv cov nplej thiab cov roj rape yog 200 μg / kg;Russia teev tias qhov tso cai ntawm zearalenone hauv durum nplej, hmoov nplej, thiab hom qoob mog yog 1000 μg / kg;Uruguay qhia tias qhov tso cai ntawm zearalenone hauv pob kws, qhov tso cai ntawm zearalenone ZEN hauv barley yog 200μg / kg.Nws tuaj yeem pom tias tsoomfwv ntawm ntau lub tebchaws tau maj mam paub txog kev puas tsuaj uas zearalenone coj los rau tsiaj thiab tib neeg, tab sis lawv tseem tsis tau mus txog qhov kev pom zoo txwv.

Kev puas tsuaj ntawmZearalenone

ZEN yog ib hom tshuaj estrogen.Kev loj hlob, kev loj hlob thiab kev loj hlob ntawm cov tsiaj txhu uas noj ZEN yuav cuam tshuam los ntawm cov tshuaj estrogen siab.Ntawm txhua tus tsiaj, npua yog qhov nkag siab tshaj plaws rau ZEN.Cov tshuaj lom ntawm ZEN rau cov noob qoob loo yog raws li hauv qab no: tom qab cov neeg laus sows raug tshuaj lom los ntawm ZEN noj, lawv lub cev xeeb tub yuav tsim txawv txav, nrog rau cov tsos mob xws li zes qe menyuam dysplasia thiab endocrine ntshawv siab;cev xeeb tub sows yog nyob rau hauv ZEN Miscarriage, yug ntxov ntxov, los yog ntau zaus ntawm malformed fetuses, stillbirths thiab tsis muaj zog fetuses yuav tshwm sim tom qab lom;lactating sows yuav txo cov kua mis ntim lossis tsis tuaj yeem tsim cov mis nyuj;Nyob rau tib lub sijhawm, piglets noj ZEN-contaminated mis nyuj kuj yuav Cov tsos mob xws li kev loj hlob qeeb vim muaj tshuaj estrogen siab, mob hnyav yuav tshaib plab thiab tuag thaum kawg.

ZEN tsis tsuas yog cuam tshuam rau cov nqaij qaib thiab tsiaj txhu, tab sis kuj muaj cov tshuaj lom neeg muaj zog.ZEN accumulates nyob rau hauv tib neeg lub cev, uas tuaj yeem ua rau cov qog nqaij hlav, ua rau DNA, thiab ua rau cov chromosomes txawv txav.ZEN tseem muaj cov teebmeem carcinogenic thiab txhawb kev nthuav dav ntawm cov qog nqaij hlav cancer hauv tib neeg cov ntaub so ntswg lossis cov kabmob.Lub xub ntiag ntawm ZEN co toxins ua rau muaj mob qog noj ntshav hauv cov nas sim.Kev sim ntau ntxiv kuj tau lees paub qhov no.Tsis tas li ntawd, qee qhov kev tshawb fawb tau kwv yees tias kev sib sau ntawm ZEN hauv tib neeg lub cev ua rau muaj ntau yam kab mob xws li mob qog noj ntshav lossis lub mis hyperplasia.

Kev txheeb xyuas txoj kev ntawmzearalenone

Vim tias ZEN muaj ntau yam kev ua qias tuaj thiab muaj kev puas tsuaj loj, ZEN txoj haujlwm kuaj xyuas yog qhov tseem ceeb tshwj xeeb.Ntawm tag nrho cov kev tshawb nrhiav ntawm ZEN, cov hauv qab no yog siv ntau dua: chromatographic ntsuas txoj kev (features: nrhiav kom muaj nuj nqis, qhov tseeb siab, tab sis kev ua haujlwm nyuaj thiab tus nqi siab heev);enzyme-txuas immunoassay (cov yam ntxwv: siab rhiab heev thiab ntau lub zog, tab sis Kev ua haujlwm yog cumbersome, lub sij hawm nrhiav tau ntev, thiab tus nqi siab);txoj kev ntsuas kub colloidal (cov yam ntxwv: ceev thiab yooj yim, tus nqi qis, tab sis qhov tseeb thiab rov ua dua yog qhov tsis zoo, tsis muaj peev xwm ua kom muaj nuj nqis);fluorescence quantitative immunochromatography (cov yam ntxwv: ceev yooj yim thiab raug kom muaj nuj nqis, zoo precision, tab sis yuav tsum tau siv cov cuab yeej, reagents los ntawm txawv manufacturers tsis universal).